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There are several possible mechanisms, including the lowering of CYP3A4 activity.

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This side effect goes away when treatment is stopped.

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A preferred dosage of Procardia XL (nifedipine GITS) is from about 10 to about 90 mg per day.

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The bioavailability of nifedipine as ADALAT CC relative to immediate release nifedipine is in the range of 84%-89%.

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All graphing and slope calculations were performed by computer, using a Cricket graph 2.

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Those skilled in the art can now appreciate from the foregoing description that the broad teachings of the present invention can be implemented in a variety of forms.

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The recommended initial dose is 10 to 20 mg twice daily.

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